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人类基因组序列草案的高分辨率辐射混合图

M Olivier1, A Aggarwal, J Allen

  • 1Stanford Human Genome Center, Stanford University School of Medicine, 975 California Avenue, Palo Alto, CA 94304, USA.

Science (New York, N.Y.)
|February 22, 2001
PubMed
概括

研究人员使用90个全基因组辐射混合体和超过4万个被测序标记站点创建了人类基因组物理地图. 这张地图有助于理解基因组组装的准确性和识别草稿序列中的差异.

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.