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相关概念视频

DNA Base Pairing02:27

DNA Base Pairing

Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
DNA Base Pairing02:27

DNA Base Pairing

Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
DNA Helicases00:55

DNA Helicases

DNA unwinding helicase enzymes are a type of motor protein. Motor proteins can translocate along filaments or polymers using energy generated from ATP hydrolysis. Helicases are involved in all the important cellular processes where DNA unwinding is required, such as DNA replication, repair, recombination, and transcription. They are present in all living organisms, but vary in their structure, function, and mechanism of action. For example, in prokaryotes, DnaB helicase binds and translocates...
DNA Topoisomerases02:02

DNA Topoisomerases

Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types.  Type I...
DNA-only Transposons02:57

DNA-only Transposons

DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...

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相关实验视频

Updated: Jun 24, 2026

Associated Chromosome Trap for Identifying Long-range DNA Interactions
14:49

Associated Chromosome Trap for Identifying Long-range DNA Interactions

Published on: April 23, 2011

在DNA中的近距离诱导的超导性.

A Y Kasumov1, M Kociak, S Guéron

  • 1Laboratoire de Physique des Solides, Associé au CNRS, Bât 510, Université Paris-Sud, 91405, Orsay, France.

Science (New York, N.Y.)
|February 24, 2001
PubMed
概括
此摘要是机器生成的。

双链DNA表现出低至1克尔文的欧姆电导率. 在数百纳米的范围内,DNA分子保持相连贯性,即使在千克尔文温度下也是如此,这表明它们有可能成为分子电线.

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CD Spectroscopy to Study DNA-Protein Interactions
06:48

CD Spectroscopy to Study DNA-Protein Interactions

Published on: February 10, 2022

Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast
09:19

Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast

Published on: March 6, 2026

相关实验视频

Last Updated: Jun 24, 2026

Associated Chromosome Trap for Identifying Long-range DNA Interactions
14:49

Associated Chromosome Trap for Identifying Long-range DNA Interactions

Published on: April 23, 2011

CD Spectroscopy to Study DNA-Protein Interactions
06:48

CD Spectroscopy to Study DNA-Protein Interactions

Published on: February 10, 2022

Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast
09:19

Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast

Published on: March 6, 2026

科学领域:

  • 分子电子学分子电子学
  • 凝聚物质物理学 凝聚物质物理学
  • 纳米技术 纳米技术

背景情况:

  • 了解DNA的电性对于分子电子学至关重要.
  • 以前的研究已经探索了DNA导电性,结果各不相同.
  • 在冷温度下研究DNA的行为对于其在量子设备中的应用至关重要.

研究的目的:

  • 在冷温度下测量双链DNA分子的导电性.
  • 为了确定DNA在广泛的温度范围内的欧姆行为和阻力.
  • 为了研究DNA中近距离诱导的超导性.

主要方法:

  • 用理工艺将DNA分子沉积在一个亚微米切片上.
  • 在/碳金属接触器之间进行了导电性测量.
  • 从室温到1克尔文进行了测量.

主要成果:

  • 发现DNA导电在室温和1凯尔文之间是欧姆级.
  • 每个DNA分子的电阻小于100千欧姆,并显示出微弱的温度依赖性.
  • 在接触点的超导过渡温度以下观察到近距离诱导的超导.

结论:

  • DNA 分子可以导电到米基尔文温度.
  • 在DNA分子中,相连贯性保持在几百纳米以上.
  • 这些发现支持DNA作为冷电子设备的组件的潜力.