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Kidney Structure01:45

Kidney Structure

The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
Fibrous Proteins00:55

Fibrous Proteins

Fibrous proteins are either long and narrow proteins or assemble to form long and thin structures. They contain repetitive units and usually consist of either alpha helices or beta sheets and, in rare cases, a mix of both. The amino acids in the primary structure often consist of repeating amino acid sequences. The role of fibrous proteins is primarily structural. Many are located in the extracellular matrix and are present in connective tissues to impart strength and joint mobility. They are...
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

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相关实验视频

Updated: Jul 12, 2026

Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
06:36

Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue

Published on: May 1, 2019

子宫纤维瘤是什么子宫纤维瘤

E A Stewart1

  • 1Center for Uterine Fibroids, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA. eastewart@partners.org

Lancet (London, England)
|February 24, 2001
PubMed
概括

子宫瘤 (纤维瘤) 是常见的良性子宫瘤,导致显著的发病率. 对纤维瘤生物学和向治疗的新研究可能会提供未来更好的治疗选择,超越手术和激素操纵.

科学领域:

  • 妇科瘤学 妇科瘤学
  • 生殖内分泌学 生殖内分泌学
  • 瘤生物学 瘤生物学

背景情况:

  • 子宫肌瘤 (纤维瘤) 是女性子宫切除术的最常见原因.
  • 纤维瘤影响高达25%的女性,导致大量出血,疼痛和生殖问题,影响生活质量并产生大量的经济成本.
  • 目前的手术和激素治疗等治疗方法都有局限性,包括复发和副作用.

研究的目的:

  • 审查目前对子宫乳腺瘤生物学和治疗选择的理解.
  • 强调需要基于证据的纤维瘤疗法的评估.
  • 探索基于分子和遗传洞察力的潜在未来治疗方法.

主要方法:

  • 审查关于子宫乳腺瘤,其临床表现和治疗方式的现有文献.
  • 分析当前的治疗策略,包括手术和激素治疗.
  • 讨论关于纤维瘤发育背后的生物机制的新兴研究.

主要成果:

  • 手术仍然是主要的治疗方法,但复发是一个重大问题.
  • 激素疗法是有效的,但受到副作用的限制,需要探索激素对抗剂.
  • 了解生长因子和基因突变的作用对于开发新疗法至关重要.

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A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia

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Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis
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Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

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相关实验视频

Last Updated: Jul 12, 2026

Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
06:36

Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue

Published on: May 1, 2019

A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia
09:12

A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia

Published on: February 3, 2023

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis
04:37

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

结论:

  • 需要对子宫瘤治疗方法进行更多基于证据的评估.
  • 用特定的对抗剂准类固醇激素环境显示出有希望.
  • 了解纤维瘤生物学方面的未来进展可能会导致创新的治疗方法.