在人体内,用内心电极导管测绘技术研究了心室内导电. 患有正常QRS和右捆分支阻塞的患者
Circulation
|May 1, 1975
概括
这项研究研究了在患有和没有右束分支阻塞 (RBBB) 的患者的静脉内导电. 研究结果显示,RBBB显著减缓了右心室激活,并可能改变左心室脱极化.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 心脏成像 - - 心脏成像
背景情况:
- 腹腔导电异常,如右束枝干阻塞 (RBBB),可能会影响心脏功能.
- 了解心室激活的序列对于诊断和管理心脏病至关重要.
研究的目的:
- 为了研究和比较QRS形态正常的患者与右束分支块 (RBBB) 患者的内腔导电时间.
- 为了确定RBBB如何影响心室不同区域的激活序列.
主要方法:
- 研究了60名患者,包括38名正常QRS患者和37名RBBB患者 (连续或诱导).
- 在特定的心室部位使用心内电极导管测量内心激活时间 (RVIT,RVA,RVOT,LVA,LVOT).
- 分析了以毫秒的激活时间,并将其与RBBB患者的QRS持续时间相关联.
主要成果:
- 与正常对照组相比,RBBB患者的右心室激活 (RVA,RVOT) 在RBBB患者中明显较慢 (P < 0.001).
- 右心室激活时间 (RVA,RVOT) 与RBBB中的QRS持续时间直接相关.
- 在RBBB患者中观察到左心室外流通道 (LVOT) 激活时间的意想不到的显著差异 (P < 0.05).
结论:
- 内心激活模式可以在导管实验室评估.
- 右心室导电与RBBB显著减缓,与QRS持续时间直接相关.
- 发展RBBB可能会导致左心室脱极化序列的改变.
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