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Updated: Jul 15, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

与囊性纤维化相关的突变中异常的CFTR依赖的HCO3-运输

J Y Choi1, D Muallem, K Kiselyov

  • 1Department of Physiology, The University of Texas Southwestern Medical Center, Dallas 75390, USA.

Nature
|March 10, 2001
PubMed
概括

囊性纤维化 (CF) 由囊性纤维化跨膜导电调节器 (CFTR) 的突变引起. 损害CFTR二碳酸盐 (HCO3-) 运输,而不仅仅是化物 (Cl-) 通道功能,对于CF病变发生至关重要.

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