促进母乳养干预试验 (PROBIT):白俄罗斯共和国的一项随机试验
M S Kramer1, B Chalmers, E D Hodnett
1Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec, Canada. mkrame@po-box.mcgill.ca
JAMA
|March 10, 2001
概括
促进母乳养显著增加了母乳养的持续时间和排他性,导致婴儿胃肠道感染和疹病例减少. 这项研究提供了有效的母乳养促进策略的证据.
科学领域:
- 公共卫生 公共卫生
- 儿科 儿科 儿科
- 营养科学 营养科学
背景情况:
- 观察性研究表明母乳养有好处,但对工业化国家的规模存在偏见.
- 这项研究解决了关于促进母乳养有效性的强有力的证据的需求.
研究的目的:
- 评估促进母乳养的干预措施对婴儿养实践的影响.
- 评估干预对胃肠道和呼吸道感染以及亚托皮性湿疹的影响.
主要方法:
- 一个集群随机试验 (促进母乳养干预试验 - PROBIT) 涉及白俄罗斯17046对母婴.
- 干预组获得了基于婴儿友好医院倡议的支持;对照组获得了通常的护理.
- 12个月的随访评估了母乳养的持续时间,排他性和感染/湿疹的发生率.
主要成果:
- 该干预措施显著增加了母乳养的持续时间和3个月和6个月的独家性.
- 在干预组中观察到胃肠道感染和亚托皮性湿疹的显著减少.
- 没有发现呼吸道感染的显著减少.
结论:
- 实验性干预有效地促进了母乳养的持续时间和独家性.
- 这项干预措施导致婴儿胃肠道感染和亚托皮性湿疹的风险降低.
- 这些发现支持开发基于证据的母乳养促进计划.
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