转录协激活剂p300结合PCNA,可能在DNA修复合成中发挥作用

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Updated: Jun 24, 2026

Advanced Confocal Microscopy Techniques to Study Protein-protein Interactions and Kinetics at DNA Lesions
12:43

Advanced Confocal Microscopy Techniques to Study Protein-protein Interactions and Kinetics at DNA Lesions

Published on: November 12, 2017

S Hasan1, P O Hassa, R Imhof

  • 1institute of Veterinary Biochemistry, University of Zürich, Switzerland.

Nature
|March 27, 2001
PubMed
概括

转录协活性剂p300与增殖细胞核抗原 (PCNA) 相互作用,这表明它在DNA修复合成中发挥作用. 这种相互作用有助于DNA损伤部位的染色质重塑,促进DNA修复.

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