盐水冷却与与心脏病发作相关的室腔心动脉冲动术的标准射频导管切除相比
K Soejima1, E Delacretaz, M Suzuki
1Cardiovascular Division, Department of Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Circulation
|April 11, 2001
概括
冷却无线电频率 (RF) 除显著改善了先前心脏病发作患者的腹腔动脉短心 (VT) 终止率. 这种增强的疗效与较大的病变产生有关,促进了成功的切除手术.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 在动物模型中,用盐水冷却的电极增强了射频 (RF) 除损伤的大小.
- 这表明,在人类中,可以改善心室动脉冲动 (VT) 终止的可能性.
研究的目的:
- 为了比较冷却射频与标准射频消化疗法在先前心脏病发作患者中终止静脉瘤的疗效.
主要方法:
- 对66名静脉瘤患者的366个除部位进行了回顾性审查.
- 废弃地点根据引进和隔离潜力进行分类.
- 采用标准射频或冷却的射频能量进行了切除.
主要成果:
- 与标准射频相比,冷却射频在地峡部位 (有或没有隔离电位) 和内环部位的VT终止率更高.
- 在冷却和标准RF之间的旁观者或外部环站点上没有观察到终止率的显著差异.
- 显著发现的P值为P=0.003和P=0.04.
结论:
- 冷却的射频除在人类心脏病中更有效地终止静脉瘤.
- 增加的疗效归因于较大的病变形成,有助于成功的切除.
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