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Updated: Jun 20, 2026

Single-Molecule Imaging of Nuclear Transport
12:13

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Published on: June 10, 2010

通过N端规则路径降解凝聚素子单元对于染色体稳定性至关重要

H Rao1, F Uhlmann, K Nasmyth

  • 1Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.

Nature
|April 20, 2001
PubMed
概括

N-end规则路径降解了一个关键的凝聚素片段,防止酵母体的染色体损失. 破坏这种途径导致不稳定和细胞死亡,突出其在基因组稳定中的关键作用.

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