概括
SDHD基因中的遗传突变与家族性染细胞瘤有关. 对于具有家族性,多重或早期发病的染细胞瘤的个体,建议对SDHD突变进行测试.
科学领域:
- 内分泌学 在内分泌学.
- 遗传学 是一个遗传学.
- 在瘤学瘤学.
背景情况:
- 家庭染细胞瘤遗传学在很大程度上是未知的.
- 亲属头部和部偏瘤与酸脱酶复合体亚单元D (SDHD) 基因突变有关.
- 在家族染细胞瘤亲属中调查SDHD是有必要的.
相关概念视频
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02:21Cancers Originate from Somatic Mutations in a Single Cell
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...