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对细菌鞭毛素的先天免疫反应是由Toll-like受体5介导的

F Hayashi1, K D Smith, A Ozinsky

  • 1Department of Immunology, University of Washington, Seattle 98195, USA.

Nature
|April 27, 2001
PubMed
概括

哺乳动物托尔样受体5 (TLR5) 检测细菌鞭毛素,这是鞭毛病原体的关键组成部分. 这种识别激活了免疫信号通路,导致细胞因子的产生和对细菌感染的有效免疫力.

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