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Updated: Aug 3, 2026

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
08:37

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog

Published on: November 5, 2014

对于 zona pellucida 诱导的青体反应,对 Cdelta4 脂酶的要求是:

K Fukami1, K Nakao, T Inoue

  • 1Department of Biochemistry, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8039, Japan. kfukami@ims.u-tokyo.ac.jp

Science (New York, N.Y.)
|May 8, 2001
PubMed
概括

脂酶C delta 4 (PLCdelta4) 对于男性生育能力至关重要. 缺少PLCdelta4的小鼠是无菌的,因为它们的精子无法完成受精所需的宏粒反应.

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A Liposome Membrane Permeability Assay for Investigating the Effects of Phosphatidylinositol Phosphate Groups on Membranotropic Action of Venom PLA210:31

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Fertilization01:38

Fertilization

During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...