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相关概念视频

Mismatch Repair01:20

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu01:29

Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu

Genetic variations significantly influence drug response through pharmacokinetics, receptor interactions, and biologic milieu modifications. Pharmacokinetic alterations impact drug metabolism and clearance, affecting efficacy and toxicity. Variants in drug-metabolizing enzymes, such as CYP2C9 and CYP2C19, alter drug activation and elimination. For example, CYP2C9 loss-of-function variants require lower warfarin doses to prevent excessive bleeding, while CYP2C19 variants reduce clopidogrel...

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相关实验视频

Updated: Jun 21, 2026

Isolation of Double Negative &#945;&#946; T Cells from the Kidney
06:56

Isolation of Double Negative αβ T Cells from the Kidney

Published on: May 16, 2014

Cd36基因的无意义突变与对严重疟疾的保护有关.

A Pain, B C Urban, O Kai

    Lancet (London, England)
    |May 30, 2001
    PubMed
    概括

    一个CD36基因突变提供了对非洲儿童严重疟疾的保护. 这一遗传发现突显了疟疾结果中的复杂宿主-寄生虫相互作用.

    科学领域:

    • 遗传学 是一个遗传学.
    • 免疫学 免疫学 免疫学
    • 传染性疾病 传染性疾病

    背景情况:

    • 研究宿主遗传因素在疟疾病原发生中的作用.
    • 专注于涉及严重疟疾中CD36的宿主-寄生虫相互作用.
    • 检查CD36基因内的特定无意义突变.

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    Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

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    Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
    07:15

    Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

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    Isolation of Double Negative &#945;&#946; T Cells from the Kidney
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    10:21

    Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

    Published on: February 21, 2018

    Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
    07:15

    Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

    Published on: August 23, 2024