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在NOD2中发生的框架转移突变与克罗恩病的易感性有关

Y Ogura1, D K Bonen, N Inohara

  • 1Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

Nature
|June 1, 2001
PubMed
概括

NOD2基因的特定突变与克罗恩病 (CD) 相关,这是一种慢性胃肠道疾病. 这种NOD2基因突变会损害对细菌成分的免疫反应,这表明CD发育的新途径.

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