在非常小的 (学龄前) 儿童中,所有喘息障碍的患病率都在增加吗?
C E Kuehni1, A Davis, A M Brooke
1Department of Child Health, University of Leicester, Leicester Royal Infirmary, Leicester, UK. claudia.kuehni@insel.ch
Lancet (London, England)
|June 19, 2001
概括
儿童喘息障碍的患病率,包括病毒性喘息,在1990年至1998年间显著增加. 这种学前喘的增加表明,除了亚托皮之外的因素正在推动儿童呼吸系统问题.
科学领域:
- 儿童呼吸系统健康问题
- 儿童喘息障碍的流行病学
- 亚托邦和喘研究的研究.
背景情况:
- 幼儿的明显喘息障碍,包括与形无关的喘障碍,存在诊断挑战.
- 调查学前喘息障碍患病率的变化可能会揭示儿童喘率上升背后的机制.
研究的目的:
- 检查8年期间在学龄前儿童中各种喘息障碍患病率的变化.
- 确定导致儿童喘患病率上升的潜在因素.
主要方法:
- 基于人口的调查,在英国莱斯特郡进行,使用家长填写的邮政问卷.
- 1990年和1998年调查的1-5岁的高加索儿童随机样本.
主要成果:
- 报告的喘息有史以来 (16%至29%),当前喘息 (12%至26%),喘诊断 (11%至19%) 和喘息治疗 (15%至26%) 显著增加.
- 在所有类型的喘息障碍中都观察到增加,包括病毒性喘息 (9%至19%) 和短暂的早期喘息 (3%至5%).
- 持续喘息的发病率从5%上升到13%,晚发喘息从6%上升到8%.
结论:
- 包括病毒性喘息在内的学龄前喘息障碍的普遍增加,指向与非图皮相关的因素.
- 这些发现表明,与过敏敏感性无关的环境或其他因素在儿童喘息的流行病学变化中发挥着作用.
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