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Updated: Jun 29, 2026

Experimental Metastasis and CTL Adoptive Transfer Immunotherapy Mouse Model
08:06

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Published on: November 26, 2010

初级免疫缺陷疾病:分子医学的一个实验模型

A Fischer1

  • 1INSERM U429, Hôpital Necker, 149 Rue de Sévres, 75015, Paris, France. fischer@necker.fr

Lancet (London, England)
|June 19, 2001
PubMed
概括

遗传学的进步改善了对原发性免疫缺陷疾病的诊断. 现在,分子探针可靠地诊断出这些遗传性免疫系统疾病中的大多数,为新疗法铺平了道路.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...