布拉迪基宁和神经生长因子从PtdIns中释放素受体(4,5) P2-介导的抑制

H H Chuang1, E D Prescott, H Kong

  • 1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94143-0450, USA.

Nature
|June 22, 2001
PubMed
概括

布拉迪基宁和神经生长因子 (NGF) 通过激活特定受体和脂酶C (PLC) 信号传递来提高疼痛敏感度. 这个过程需要VR1热激活离子通道,揭示了疼痛过敏的分子机制.

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