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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

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在基因毒性应激反应中,需要ATR/ATM介导的人类Rad17的酸化

S Bao1, R S Tibbetts, K M Brumbaugh

  • 1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Nature
|June 22, 2001
PubMed
概括

基因毒性压力激活细胞循环检查点进行DNA修复. 人类Rad17 (hRad17) 通过ATM/ATR激酶的酸化对于这种DNA损伤反应至关重要,它调节细胞循环停止和DNA修复信号.

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