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Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy
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解蛋白-2 负面调节胰岛素分泌,是肥胖,β细胞功能障碍和2型糖尿病之间的主要联系

C Y Zhang1, G Baffy, P Perret

  • 1Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 99 Brookline Avenue, Boston, MA 02115, USA.

Cell
|July 7, 2001
PubMed
概括

解蛋白-2 (UCP2) 负面调节β细胞的胰岛素分泌. 在肥胖小鼠中去除UCP2恢复了胰岛素分泌和降低了血糖,将UCP2与2型糖尿病联系起来.

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