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相关概念视频

Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Time and frequency -Domain Interpretation of Phase-lag Control01:21

Time and frequency -Domain Interpretation of Phase-lag Control

Phase-lag controllers are widely used in control systems to improve stability and reduce steady-state errors. A dimmer switch controlling the brightness of a light bulb serves as a practical example of phase-lag control, gradually adjusting the bulb's brightness. Mathematically, phase-lag control or low-pass filtering is represented when the factor 'a' is less than 1.
Phase-lag controllers do not place a pole at zero, but instead influence the steady-state error by amplifying any finite,...

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相关实验视频

Updated: Jul 11, 2026

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice
17:45

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

Published on: February 26, 2012

泰奥菲林和托巴尔比塔尔作为大鼠中昼夜时间控制器的时代型作用.

C F Ehret, V R Potter, K W Dobra

    Science (New York, N.Y.)
    |June 20, 1975
    PubMed
    概括
    此摘要是机器生成的。

    西奥菲林和巴尔比塔尔可以重置老鼠的体温节奏. 取决于时间,这些药物会导致相延迟或进展,将它们确定为改变生物时间的时代生物.

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    Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents
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    Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
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    相关实验视频

    Last Updated: Jul 11, 2026

    T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice
    17:45

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    Published on: February 26, 2012

    Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents
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    Published on: January 24, 2013

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    Published on: February 26, 2014

    科学领域:

    • 时间生物学 时间生物学
    • 药理学 药理学 是一个学科.
    • 生理学 生理学 生理学

    背景情况:

    • 循环节律调节生理过程,包括体温.
    • 众所周知,西奥菲林和潘托巴比塔尔具有各种药理学效应.

    研究的目的:

    • 为了研究西奥菲林和巴比他对大鼠深层体温节律的影响.
    • 为了确定这些药物是否可以归类为chronobiotics.

    主要方法:

    • 通过遥测来监测大鼠的深层体温节奏.
    • 根据昼夜周期,西奥菲林和潘托巴比塔尔在不同的时间点被使用.

    主要成果:

    • 这两种药物在活性阶段的早期服用时都会导致相位延迟.
    • 当在热量峰值后给予时,西奥菲林会导致相位进步,而托巴比他则没有.
    • 这表明基于药物和时间的不同阶段转换能力.

    结论:

    • 泰奥菲林和巴巴比塔尔可以预测地改变昼夜节律.
    • 这些药物被认定为时代生物制剂,能够重构生物时间结构.