相关实验视频
Updated: Jun 24, 2026

11:49
Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
Published on: May 2, 2013
可能的艺术:适应性免疫系统中的系统控制
1Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA. rgermain@nih.gov
概括
免疫系统的免疫系统.
科学领域:
- 免疫学 免疫学 免疫学
- 系统生物学 系统生物学
- 计算生物学 计算生物学
背景情况:
- 免疫系统的细胞和分子组成部分得到了充分的研究.
- 一个全面的系统层面的免疫系统动态的理解正在出现.
- 目前的知识缺乏对免疫系统复杂性的整体观点.
研究的目的:
- 为免疫系统功能提出系统工程视角.
- 突出免疫反应中随机性,放大,反和异质性的作用.
- 确定免疫系统操纵健康和疾病的新途径.
主要方法:
- 概念框架的发展.
- 通过系统工程镜头分析免疫系统特性.
- 文献综述和理论建模 (隐含).
主要成果:
- 随机事件显著影响免疫系统的行为.
- 放大机制对于有效的免疫反应至关重要.
- 反控制和细胞相互作用的异质性塑造了免疫系统的特性.
- 系统视图解释了免疫的新兴特性.
结论:
- 了解随机性,放大,反和异质性是理解免疫功能的关键.
- 这种系统方法为免疫发育和功能障碍提供了新的见解.
- 从这个角度来看,新的预防和治疗策略可以出现.
相关概念视频
What is the Immune System?
Overview
Cell-mediated Immune Responses
Overview
Introduction to Innate and Adaptive Immunity
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
Special Features of Adaptive Immunity
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
Antigens Involved in Adaptive Immunity
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Immune Response Against Viral Pathogens
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...

