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Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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超冷水中的芳香环翻转:对基于NMR的蛋白质结构生物学的影响

J J Skalicky1, J L Mills, S Sharma

  • 1Contribution from the Department of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA.

Journal of the American Chemical Society
|July 18, 2001
PubMed
概括

超冷蛋白溶液显著减缓了BPTI中的芳香环翻转,使得在0°C以下进行详细的NMR研究成为可能. 这种方法增强了结构生物学,允许精确测量蛋白质动态在一个不受干扰的水环境.

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