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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Published on: July 28, 2017

含有异黄素和异酸丁的RNA复合体的稳定性和结构

X Chen1, R Kierzek, D H Turner

  • 1Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, USA.

Journal of the American Chemical Society
|July 18, 2001
PubMed
概括

在RNA复合体中的异花素 (iG) 和异花素 (iC) 替代物通常会增强稳定性,而稳定效应则取决于序列. 这一发现对于理解核酸热力学和结构性质至关重要.

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