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Updated: Jun 15, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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1,3-二氧化的分池合成导致单个化合物的排列库存溶液,足以进行多个表型和蛋白质结合试验

S M Sternson1, J B Louca, J C Wong

  • 1Harvard Institute of Chemistry and Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|July 18, 2001
PubMed
概括

研究人员开发了一种新的分池合成方法,用于创建多样化的小分子库. 这种方法通过生产用于生物测试的化合物,使化学遗传学研究有效.

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相关概念视频

¹H NMR: Complex Splitting01:13

¹H NMR: Complex Splitting

A proton M that is coupled to a proton X results in doublet signals for M. However, NMR-active nuclei can be simultaneously coupled to more than one nonequivalent nucleus. When M is coupled to a second proton A, such as in styrene oxide, each peak in the doublet is split into another doublet.
Splitting diagrams or splitting tree diagrams are routinely used to depict such complex couplings. While drawing splitting diagrams, the splitting with the larger coupling constant is usually applied first.