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第一个和第二代的整体合成的teicoplanin甘氨酸

D L Boger1, S H Kim, Y Mori

  • 1Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Journal of the American Chemical Society
|July 18, 2001
PubMed
概括

研究人员开发了一种更高效的整体合成,用于teicoplanin aglycon,一个关键的抗生素成分. 这种改进的方法涉及到环闭序的战略性变化,增强了这种复杂分子的立体选择性和整体产量.

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