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Updated: Jun 30, 2026

Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor
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Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor

Published on: March 21, 2018

通过与氨酸结合的酶选择性DNA线程动力学.

B Onfelt1, P Lincoln, B Nordén

  • 1Department of Physical Chemistry, Chalmers University of Technology, S-412 96 Gothenburg, Sweden.

Journal of the American Chemical Society
|July 18, 2001
PubMed
概括

状双间隔器显示出不同的DNA结合动态. 虽然这两种酶体都强烈地结合了DNA,但它们的解离率和盐的依赖性有很大差异,这表明了复杂的结构变化.

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相关概念视频

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...