对心脏病妇女怀孕结果的前性多中心研究
S C Siu1, M Sermer, J M Colman
1University of Toronto, Toronto, Ontario, Canada. Sam.Siu@uhn.on.ca
Circulation
|August 2, 2001
概括
患有心脏病的女性怀孕对母亲和新生儿都有重大风险,即使有高级护理. 预测风险指数有助于识别怀孕期间心脏并发症风险较高的女性.
科学领域:
- 心脏病学 心脏病学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生殖健康 生殖健康
背景情况:
- 患有心脏病的孕妇的孕产妇和新生儿风险还没有得到很好的定义.
- 综合性产前护理至关重要,但结果需要进一步阐明.
研究的目的:
- 确定患有心脏病的孕妇的孕产妇和新生儿风险.
- 为了确定产妇心脏并发症和新生儿并发症的预测因素.
主要方法:
- 预计将招募562名患有心脏病的孕妇.
- 对599例怀孕 (不包括流产) 结果的分析.
- 确定母亲和新生儿并发症的独立预测因子.
主要成果:
- 13%的怀孕是由母亲的心脏事件 (肺,心律失常,中风,心脏病死亡) 导致的.
- 产妇心脏并发症的关键预测因素包括先前的心脏事件,功能类差,蓝色病,左心脏阻塞和左心室静脉功能障碍.
- 新生儿并发症发生在20%的怀孕中,与功能类不良,蓝斑症,左心阻塞,抗凝,吸烟和多胎妊娠有关.
结论:
- 患有心脏病的女性怀孕带来了相当大的心脏和新生儿风险,即使是最优的护理.
- 经过验证的风险指数可以有效预测母亲的心脏风险.
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