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红蛋白介导的神经保护包括Jak2和NF-kappaB信号级联之间的交叉对话

M Digicaylioglu1, S A Lipton

  • 1Center for Neuroscience and Aging Research, The Burnham Institute, La Jolla, CA 92037, USA.

Nature
|August 9, 2001
PubMed
概括

红色素 (EPO) 预调剂通过激活神经元中的EPO受体,保护大脑细胞免受损伤. 这触发了一种新的信号通路,涉及Janus kinase-2 (Jak2) 和核因子-kappaB (NF-kappaB),防止神经元死亡.

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