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Updated: Jun 21, 2026

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对随机和非随机研究中治疗效应证据的比较

J P Ioannidis1, A B Haidich, M Pappa

  • 1Division of Clinical Care Research, New England Medical Center, Box 63, 750 Washington St, Boston, MA 02111, USA. JLau1@lifespan.org

JAMA
|August 22, 2001
PubMed
概括

随机和非随机研究显示出良好的相关性,但非随机研究往往报告了更大的治疗效果. 发生了差异,特别是非前性设计,影响了医疗干预研究.

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