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Disturbances in Heart Rhythm01:29

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Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
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在患有永久起器或可植入心脏转换器-除器的患者中患有黄金葡萄球菌菌病.

A L Chamis1, G E Peterson, C H Cabell

  • 1Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

Circulation
|August 29, 2001
PubMed
概括

心脏器件感染 (CDI) 在患有黄金菌杆菌菌病 (SAB) 的患者中很常见,影响了总体45.4%的病例. 早期SAB显示出更高的感染率,通常具有临床症状,而晚期SAB的感染率较低,但仍有显著的设备参与.

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科学领域:

  • 心脏病学 心脏病学
  • 传染性疾病 传染性疾病
  • 医疗器械技术 医疗器械技术

背景情况:

  • 心脏器官感染 (CDI) 是一种严重的并发症.
  • 细菌病患者中CDI的发病率尚不清楚.
  • 这项研究侧重于心脏器械患者的黄金杆菌菌菌病 (SAB).

研究的目的:

  • 为了确定患有心脏起器或植入式心脏转换器-除器的患者中CDI的发病率,这些患者会发展SAB.
  • 分析SAB和CDI开发时间之间的关系.
  • 评估这些患者中CDI的临床表现.

主要方法:

  • 长达6年的SAB和心脏器械成年患者的前性队列研究.
  • 确认和可能的CDI病例的评估.
  • 分析早期 (<1年) 与晚期 (>=1年) 的SAB.

主要成果:

  • 总体确认的CDI发生率为45.4% (15/33).
  • 早期SAB (<1年) 的CDI率为75% (9/12).
  • 晚期SAB (>=1年) 的确诊CDI率为28.5% (6/21) 和可能CDI率为43% (9/21).
  • 60%的确诊的CDI病例没有表现出局部感染迹象.

结论:

  • 在SAB和心脏器械患者中,CDI的发病率很高.
  • 身体检查和心声回声不能排除CDI.
  • 早期SAB通常涉及具有临床症状的设备;晚期SAB具有较不明显的局部症状,但仍有显著的设备参与 (>28%).