孕期孕产妇的能量储存和饮食组成 计划 青少年血压 青少年血压
L S Adair1, C W Kuzawa, J Borja
1Department of Nutrition, Schools of Public Health and Medicine, University of North Carolina, Chapel Hill, NC 27516-3997, USA. linda_adair@unc.edu
Circulation
|August 29, 2001
概括
怀孕期间母亲的营养会影响青少年的血压 (BP). 特定的饮食成分和母体脂肪储存会影响后代的血压,强调产前营养对长期心血管健康的重要性.
科学领域:
- 营养流行病学 营养流行病学
- 健康和疾病的发育起源 (DOHaD)
- 心血管健康 心血管健康
背景情况:
- 胎儿营养不良与生命后期血压 (BP) 的编程有关.
- 现有的流行病学研究使用出生体重作为胎儿营养不良的代理,缺乏关于母亲营养因素的具体性.
- 确定精确的母亲营养影响对于理解长期BP编程至关重要.
研究的目的:
- 研究怀孕期间母亲的营养与青少年血压之间的关系.
- 检查母亲的饮食成分 (能量,蛋白质,脂肪) 和母亲的脂肪对后代的影响BP.
- 评估婴儿出生体重与母亲营养和青少年BP相关的作用.
主要方法:
- 2026年菲律宾青少年的前性队列研究 (Cebu纵向健康和营养调查).
- 在怀孕期间评估的母亲营养状况 (约. 怀孕30周) 包括饮食摄入量和三肌皮厚度.
- 使用回归模型测量和分析青少年的缩和腹缩血压 (SBP和DBP),控制混因素.
主要成果:
- 母亲三肌皮厚度与男孩的SBP和男女的DBP相反相关.
- 母亲的蛋白质摄入与男孩的SBP相反;母亲的脂肪摄入与女孩的SBP和DBP相反.
- 母亲的营养因素部分减弱了男孩出生体重和SBP之间的反向关系.
结论:
- 怀孕期间母亲的饮食成分显著影响后代的青少年血压.
- 孕产妇皮下脂肪储存 (三头皮皮层厚度) 与长期后代血压调节有关.
- 这些发现强调了母亲的营养和身体成分在规划胎儿心血管健康中的关键作用.
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