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Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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在循环核酸门通道开通期间的旋转运动

J P Johnson1, W N Zagotta

  • 1Howard Hughes Medical Institute & Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle 98195, USA.

Nature
|August 31, 2001
PubMed
概括

离子 (Ni2+) 调节循环核酸门 (CNG) 通道,对于感官信号来说至关重要. 在C-链接器区域的特定胺残留物决定了Ni2+是否增强或抑制通道活动,揭示了对关门机制的洞察力.

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