在设计的β-hairpin中,跨链侧链 - 侧链相互作用:横向和对角对联的意义

F A Syud1, H E Stanger, S H Gellman

  • 1Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.

概括

链间侧链接触显著稳定了β-sheet结构. "侧面"的疏水相互作用和"对角"的接触,由β-sheet扭曲引起,增强β-hairpin的稳定性.

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