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蓝素A2与d ((CGCGAATTCGCG) 2的相互作用的化学和结构特征2.高效的,可在没有结构重组的情况下获得的双链DNA裂变

M V Keck1, R A Manderville, S M Hecht

  • 1Department of Chemistry, University of Virginia, Charlottesville, Virginia 22901, USA.

Journal of the American Chemical Society
|September 6, 2001
PubMed
概括

抗癌药物白素A2通过准特定部位,导致DNA双链断裂. 这项研究揭示了白素如何与DNA相互作用以诱导这些断裂,并提供了对其作用机制的见解.

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