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在SCN5A相关的心律失常综合征中,flekainide作用的关门依赖机制

P C Viswanathan1, C R Bezzina, A L George

  • 1Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee, USA.

Circulation
|September 6, 2001
PubMed
概括

心脏通道 (SCN5A) 突变导致LQT3和布鲁加达综合征. 这些突变中的非激活门缺陷会增加对弗莱卡尼德的敏感性,可能导致危险的心律失常.

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