在一个美国印第安人社区的农村地区,社区获得的抗甲素的金黄色葡萄球菌 (Staphylococcus aureus)
A V Groom1, D H Wolsey, T S Naimi
1Indian Health Service National Epidemiology Program, 5300 Homestead Rd NE, Albuquerque, NM 87110, USA.
JAMA
|September 18, 2001
概括
社区获得的甲素耐药黄金葡萄球菌 (MRSA) 感染正在农村地区出现,可能取代对甲素敏感的黄金葡萄球菌 (MSSA). 这项研究记录了农村美洲印第安人社区社区MRSA发生情况和风险因素.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 微生物学 微生物学
背景情况:
- 长期以来,耐甲基西林黄金葡萄球菌 (MRSA) 与医疗保健机构有关.
- 最近在健康儿童中发生的严重MRSA感染表明,社区获取正在增加.
- 这项研究调查了农村社区环境中的MRSA.
研究的目的:
- 为了记录社区获得的MRSA感染的发病率.
- 为了比较社区获得的MRSA风险因素与对甲素敏感的黄金色素 (MSSA) 的风险因素.
- 分析MRSA菌株的遗传相关性.
主要方法:
- 使用医疗记录审查的回顾性队列研究.
- 在一个美国中西部农村印第安人社区的印第安人卫生服务机构进行的研究.
- 分析包括MRSA分类,风险因素比较和脉冲场凝电泳 (PFGE) 以确定菌株类型.
主要成果:
- 在112个金黄色葡萄球菌分离物中,62%是MRSA,45%是MSSA.
- 很大一部分 (74%) 的MRSA感染是社区获得的.
- 在社区获得的MRSA和MSSA之间没有发现风险因素的显著差异.
- PFGE显示,大多数社区获得的MRSA菌株与临床病房菌株有克隆关系,并且与它们不同.
结论:
- 社区获得的MRSA似乎是这个农村社区的主导菌株,可能取代MSSA.
- 研究结果表明,MRSA在美国农村社区广泛传播,超出医院范围.
- 抗微生物敏感性和菌株类型支持MRSA在非诺索科米亚环境中的广泛存在.
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