在高风险自发早产妇女中期内超声波
1Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 619 19th St S, OHB 458, Birmingham, AL 35249-7333, USA. johnowen@uab.edu
JAMA
|September 19, 2001
概括
在怀孕16至18周之间通过超声波检测出宫长度的缩短,预示着高风险女性的早产. 到23周的连续测量可以提高自发早产预测的准确性.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 诊断性的超声波检查
背景情况:
- 宫长度缩短是自发早产的已知危险因素.
- 这种风险显而易见的妊娠时间尚未确立.
研究的目的:
- 为了确定16至18周6天怀孕期间的子宫超声波发现是否预测自发早产.
- 评估是否连续的子宫评估到23周6天提高高风险妇女的预测.
主要方法:
- 一项盲目的观察性研究,涉及183名高风险的单子妊娠妇女.
- 每隔2周进行一次内阴道超声波检查,测量宫长度,并注意到道和动态缩短.
- 怀孕35周之前的自发早产是主要结果,通过宫长度切线进行分析.
主要成果:
- 初始扫描时子宫长度<25毫米 (16-18周6天) 导致自发早产风险增加3.3倍.
- 连续测量宫长度,特别是观察到的最短长度,与单次测量相比,显著改善了预测.
- 在连续评估中使用最短观察到的宫长度时,自发早产的相对风险增加到4.5.
结论:
- 在怀孕16周到18周6天之间对子宫长度的内阴声学评估可以预测自发早产.
- 增加最初的宫长度测量,并连续评估至23周6天,可以提高高风险人群的预测准确性.
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