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Updated: Jun 14, 2026

Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)
10:05

Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)

Published on: January 20, 2016

具有较低cmc的可分化阴离子洗剂将等离子体DNA凝结成纳米粒子,并在培养物中转移细胞

E Dauty1, J S Remy, T Blessing

  • 1Laboratoire de Chimie Génétique associé CNRS/Université Louis Pasteur de Strasbourg, Faculté de Pharmacie BP 24, 67401 Illkirch, France.

Journal of the American Chemical Society
|September 20, 2001
PubMed
概括

研究人员开发了新型的阴离子醇清洁剂,以创建紧,稳定的DNA纳米粒子,以有效地传递基因. 这些35nm粒子显示出增强体内扩散和细胞吸收的前景.

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