年龄小于5岁儿童中关节置换后的长期存活率:一个多机构研究
C A Caldarone1, G Raghuveer, C B Hills
1Department of Surgery, University of Iowa College of Medicine, Iowa City, IA, USA. christopher-caldarone@uiowa.edu
Circulation
|September 25, 2001
概括
在幼儿中进行儿科心肌置换 (MVR) 的结果比以前想象的要好. 早期死亡率可以通过诊断和膜大小来预测,晚期死亡率较低,有助于治疗决策.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心脏外科手术 心脏外科手术
- 生物医学工程 生物医学工程
背景情况:
- 在5岁以下的儿童中,假肢门置换 (MVR) 的结果尚未明确,通常被认为是不良的.
- 本研究回顾了儿科心脏护理联盟从1982年至1999年的经验.
研究的目的:
- 评估5岁以下儿童的假肢 mitra 置换 (MVR) 的短期和长期结果.
- 在这个患者群体中确定死亡率和重新手术的预测因素.
主要方法:
- 一项对176个对139名年龄小于5岁的患者进行的关节置换手术 (MVR) 的回顾性审查.
- 随访时间中位数为6.2年,完成率为96%.
- 多变量分析被用来确定死亡的预测因素.
主要成果:
- 患者在1,5年和10年的生存率分别为79%,75%和74%.
- 并发症包括心脏阻塞 (16%),内心炎 (6%),血栓形成 (3%) 和中风 (2%).
- 早期死亡的预测因素包括完整的心房道,肖恩综合征和假肢的大小与重量的比率增加.
结论:
- 儿科中枢置换术 (MVR) 后的早期死亡率可以通过诊断和假肢尺寸与体重的比率来预测.
- 晚期死亡率很低,5年后无需重新手术的死亡率为81%.
- 这些发现可以帮助指导治疗决策在MVR和息策略之间在幼儿中.
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