周围动脉疾病的腿部症状:相关的临床特征和功能障碍
M M McDermott1, P Greenland, K Liu
1Department of Medicine, Northwestern University Medical School, Chicago, IL, USA. mdm608@northwestern.edu
JAMA
|October 5, 2001
概括
周围动脉疾病 (PAD) 除了间歇性关节障碍 (IC) 之外,还表现出各种腿部症状. 这些多样化的症状与PAD患者的不同功能限制和并发症相关.
科学领域:
- 血管医学 血管医学
- 临床研究 临床研究
- 患者的运作 患者的运作
背景情况:
- 周围动脉疾病 (PAD) 经常表现为腿部症状,超出了经典的间歇性关节障碍 (IC).
- 许多PAD患者无症状或存在非典型的腿部投诉.
- 了解腿部症状的范围对于全面的PAD管理至关重要.
研究的目的:
- 在患有PAD的患者中,确定与广泛的腿部症状相关的临床特征和功能限制.
- 在各种PAD症状表现中区分功能障碍.
- 探索伴随性疾病对PAD腿部症状的影响.
主要方法:
- 这是一项涉及460名PAD患者和130名对照者的横截面研究.
- 使用脚-手臂指数 (ABI) 来诊断PAD.
- 通过6分钟的步行,体力活动监测器,椅子提升,平衡测试,步行速度和验证的问卷来评估功能状态.
主要成果:
- 与对照组相比,所有PAD组都表现出较差的功能.
- 非典型的炼性腿部疼痛组表现出比IC组更好的功能.
- 患有休息和运动时腿部疼痛的患者表现出显著的功能缺陷和更高的并发病率 (例如糖尿病,脊柱狭窄症).
结论:
- 周围动脉疾病 (PAD) 涵盖了比间歇性关节障碍 (IC) 更广泛的腿部症状.
- 伴随性疾病可能有助于在PAD中观察到的各种腿部症状.
- 功能障碍在所有PAD症状组中普遍存在,严重程度因症状类型而异.
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