副交感神经活动解释了高海拔地区运动心率的降低
R Boushel1, J A Calbet, G Rådegran
1Copenhagen Muscle Research Center, Rigshospitalet, University of Copenhagen, Denmark. boushel@alcor.concordia.ca
Circulation
|October 10, 2001
概括
增强的副交感活动会在高空运动期间降低心率,但不会影响心脏输出. 缺氧似乎在高空运动期间减弱心脏输出.
科学领域:
- 心血管生理学心血管生理学
- 高度生理学 高度生理学
- 运动生理学 运动生理学
背景情况:
- 慢性缺氧会在运动期间降低心率 (HR) 和心率 (Q).
- 副交感活动在海拔高度的HR减少中的作用尚不清楚.
- 偏交对高空Q和氧气运输的影响尚未研究.
研究的目的:
- 为了研究副交感神经活动在高空运动期间调节HR和Q中的作用.
- 确定阴道阻塞对慢性缺氧运动心血管反应的影响.
主要方法:
- 七个健康的低地人居住在>/=5260米9周.
- 测量HR,Q,氧气吸收,平均动脉压和腿部血流是在休息和运动周期期间进行的.
- 通过在海平面 (SL) 和高海拔 (ALT) 上使用糖烯酸盐诱导阴道阻塞.
主要成果:
- 在ALT时,与SL相比,糖酸盐显著增加了休息和运动HR.
- 阴道阻塞在ALT时恢复了最大HR至SL值,但没有影响Q.
- 呼吸补充氧气 (FIO(2) =0.55) 在运动高峰时恢复了Q和功率输出到SL值.
结论:
- 增加的副交感神经活动有助于在高空运动期间降低HR.
- 副交感活动不会影响高海拔地区的心脏输出.
- 氧气恢复研究表明,运动期间心脏输出因缺氧而减弱.
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