对SOFA评分进行序列评估,以预测重症患者的结果
F L Ferreira1, D P Bota, A Bross
1Department of Intensive Care, Erasme University Hospital, Route de Lennik, 808, B-1070 Brussels, Belgium. jlvincen@ulb.ac.be
JAMA
|October 12, 2001
概括
重复序列性器官衰竭评估 (SOFA) 在ICU中的得分预测患者的死亡率. 在48小时内增加SOFA分数表明至少50%的死亡风险,无论最初的分数如何.
科学领域:
- 关键护理医学 关键护理医学
- 预测生物标志物 预测生物标志物
- 重症监护病房的结果
背景情况:
- 器官功能障碍是重症患者的关键因素.
- 评估器官功能障碍的趋势有助于预测结果.
研究的目的:
- 评估重复序列性器官衰竭评估 (SOFA) 评分对预测重症监护室 (ICU) 患者死亡率的有用性.
- 为了确定SOFA分数趋势是否提供预测价值.
主要方法:
- 对352名ICU患者进行前性观察队列研究.
- 索法分数计算在录取和每48小时一次.
- 与死亡率相关的初始,最高,平均和Delta-SOFA分数的分析.
主要成果:
- SOFA分数 (初始,最高,平均) 与死亡率有很强的相关性.
- 最高的SOFA分数显示了ROC曲线 (0.90) 下的最大面积.
- 在96小时内增加的SOFA得分预测死亡率>50%,下降的得分预测死亡率<27%.
结论:
- 在ICU中的顺序SOFA评分评估提供了有价值的预后信息.
- 平均和最高的SOFA分数是有效的结果预测器.
- 在前48小时内SOFA得分上升独立预测高死亡风险.
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