怀孕测试与预期的月经期有关的自然限制
A J Wilcox1, D D Baird, D Dunson
1Epidemiology Branch, MD A3-05, National Institute of Environmental Health Sciences, Durham, NC 27709, USA. wilcox@niehs.nih.gov
JAMA
|October 12, 2001
概括
怀孕测试可能会错过10%的早期怀孕在错过月经的第一天. 为了准确的早期怀孕检测,请考虑在一周后进行测试,以提高灵敏度.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 临床化学 临床化学
- 人类繁殖人类的繁殖.
背景情况:
- 标准怀孕测试建议在错过月经的第一天使用.
- 早期怀孕检测受到囊胚细胞植入时间的限制.
- 排卵的变化意味着植入时间相对于预期的月经不同.
研究的目的:
- 为了估计怀孕测试的最大查灵敏度,在月经错过的第一天.
- 为了考虑到排卵和植入时间的自然变化.
主要方法:
- 在北卡罗来纳州进行了基于社区的前性队列研究 (1982-1986).
- 221名21至42岁的健康女性计划怀孕.
- 序列尿样检测人类胆管性腺激素 (hCG),以确定相对于预期月经的植入日.
主要成果:
- 10% (14/136) 的临床怀孕在错过月经的第一天没有植入.
- 据估计,hCG测试的最大查灵敏度在错过月经的第一天为90%.
- 在错过月经的第一天一周后,敏感度增加到97%.
结论:
- 10%的临床怀孕在月经错过的第一天无法通过高度敏感的hCG测试检测到.
- 由于测试的局限性,当前商业测试的实际检测率可能更低.
- 错过月经后一周进行测试可以提高怀孕检测率.
相关概念视频
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