骨髓移植后的生存率来自细胞巨乳病毒阳性兄弟捐赠者
Lancet (London, England)
|October 13, 2001
概括
捐赠细胞巨乳病毒的血清阳性改善了接受骨髓移植的白血病患者的生存率,特别是在HLA-A2阳性接受者中. 这表明细胞巨乳病毒特异性T细胞增强了移植与白血病的活性.
科学领域:
- 免疫学 免疫学 免疫学
- 血液学 血液学 血液学
- 在瘤学瘤学.
背景情况:
- 研究了103名白血病患者接受HLA相同的兄弟骨髓移植的供体细胞巨髓病毒 (CMV) 血清状态对结果的影响.
- 专注于HLA-A2限制在T细胞活动中对CMV和白血病细胞的作用.
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