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在培养的神经元和瘤细胞上,聚α 2,8-酸表达的小分子调节器

L K Mahal1, N W Charter, K Angata

  • 1Department of Chemistry, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|October 13, 2001
PubMed
概括

研究人员发现,N-butanylmannosamine (ManBut) 可以反向抑制多-α2,8-酸 (PSA) 表达. 这种小分子通过代谢途径破坏PSA生物合成,为研究PSA介导事件提供了一个新的化学工具.

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