与静脉内超声指导相比,分数流量储备用于优化支架部署的血管内超声指导
1Stanford University Medical Center, Stanford, CA, USA. wfearon@stanford.edu
Circulation
|October 17, 2001
概括
分流储备 (FFR) 可以表明支架部署不足于最佳,但0.96或更高的值不能保证最佳结果. 较高的腺剂量可以提高FFR准确度,以评估冠状动脉支架.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 分流储备 (FFR) 是评估冠状动脉支架部署的拟议方法.
- 血管内超声波 (IVUS) 是目前评估支架扩张的标准.
研究的目的:
- 将FFR的疗效与IVUS标准进行比较,以优化冠状动脉支架部署.
- 为了确定FFR的诊断特征,预测不理想的支架扩张.
主要方法:
- 一个前性的多中心试验,涉及84名冠状动脉病变的稳定患者.
- 进行了冠状动脉支架部署,使用压力线和冠状动脉内腺素测量FFR.
- 使用IVUS来评估支架扩张,并计算FFR的诊断特征.
主要成果:
- 一个FFR切线<0.96显示了最高的预测准确性 (62%) 通过IVUS.suboptimal支架扩张.
- 在FFR>=0.96时,灵敏度为75%,特异性为58%,预测精度为62%.
- 较高的冠心腺剂量 (>30微克) 显著改善了诊断性能.
结论:
- 在支架后的FFR<0.96预测了基于IVUS标准的低于最佳的结果.
- 一个FFR>=0.96不能可靠地预测一个最佳的支架结果.
- 增加的冠状腺素剂量可以提高FFR准确度,用于评估支架部署.
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