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希斯脱乙酶抑制剂可以阻止多重谷氨酸依赖于多索菲拉菌的神经退行

J S Steffan1, L Bodai, J Pallos

  • 1Department of Psychiatry and Human Behavior, Gillespie 2121, University of California, Irvine, California 92697, USA.

Nature
|October 19, 2001
PubMed
概括

扩展的多重胺蛋白质会导致神经退行性疾病. 抑制胰岛素脱乙酶 (HDAC) 可以逆转神经元损伤并降低疾病模型中的致死率,提供一种潜在的治疗方法.

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