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Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
12:06

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines

Published on: November 25, 2017

通过两个莱克的分子识别sialyl Lewis (x) 和相关的糖化物

T Haselhorst1, T Weimar, T Peters

  • 1Institut für Chemie, Medizinische Universität zu Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.

Journal of the American Chemical Society
|October 25, 2001
PubMed
概括

这项研究调查了sialyl Lewis (x),Lewis (x) 和alpha-L-Fuc-{1-->3) -beta-D-GlcNAc与莲花四角虫学蛋白A (LTL-A) 和阿勒亚兰地亚聚素 (AAA) 的结合. 研究人员发现,L-糖残留是结合的关键,在莱克复合体中观察到不同的方向.

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