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Updated: Jul 10, 2026
10:33
Research and Development of High-performance Explosives
Published on: February 20, 2016
一个新的气球可扩展的玛发射 (103) Pd) 支架无法防止边缘效应
C Hehrlein1, J J DeVries, A Arab
1Department of Cardiology, University of Freiburg, and the Forschungszentrum Karlsruhe, Germany. hehrlein@med1.ukl.uni-freiburg.de
Circulation
|November 7, 2001
概括
新型帕拉-103支架减少了支架内增生,但仍然引起了边缘效应. 这些放射性同位素支架表明,无论用于支架浸的同位素如何,边缘效应都可能发生.
科学领域:
- 心血管研究的心血管研究.
- 生物医学工程 生物医学工程
- 放射学 放射学是一门学科.
背景情况:
- 气球可扩展β颗粒发射 (32) P) 支架可以减少新极端增生症,但会引起边缘效应.
- 边缘效应表现为膜在支架边缘之外变窄.
研究的目的:
- 研究新的玛发射同位素 (103) Pd) 支架,以减轻边缘效应.
- 评价 (103) Pd 支架在减少新极端增生和边缘效应方面的性能.
主要方法:
- 在24只子中进行前性研究,使用18毫米 (103) Pd支架在20毫米气球上.
- 血管造影和组织造型测量评估了1个月后的新极端增生症,血管重塑和晚期光线损失.
- 控制和1-,2-,4-mCi (103) Pd支架植入下动脉,没有前或后扩张.
主要成果:
- 在所有活动 (P<0.05) 中,通过 (103) Pd 支架抑制了支架内晚期光量损失.
- 边缘效应,以晚期的光量损失为特征,发生在 (103) Pd 支架的边缘.
- 边缘效应与高气球/动脉比率,过度伸展损伤,新极端增生症和较高活动时负面血管改造有关.
结论:
- 放射性同位素支架植入可以导致边缘效应,无论选择的同位素.
- (103) Pd 支架在减少支架内增生方面表现有前途,但不能消除边缘效应.
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