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格拉米西丁S合成酶的启动模块PheATE的基质识别和选择

L Luo1, M D Burkart, T Stachelhaus

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|November 8, 2001
PubMed
概括

非核糖体合成酶的PheATE启动模块激活L-氨酸和其他氨基酸. 表皮化域作为一个守门员,控制D-phenylalanine的形成,用于gramicidin S的合成.

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